Isaac Jeanes & Co. was a mercantile house in Philadelphia. The collection consists of letters to the company, chiefly from Chamberlain, Robinson & Co., James Robinson, and Chamberlain & Phelps, all merchants in New York, N.Y., and James L. Taylor and Lewis J. Cassan, masters of ship WILLIAM J. MORRIS and clipper ship ARAMINGO, respectively.

Included is a ledger (1852-1854) including accounts with ships A.M. LAWRENCE, MONTAUK, and OCEANA, the brig HARRIET, and barks ANTONIETTA, C.L. BEVAN, EMMA LINCOLN, JOHN WELSH, and POWHATTAN.

There is also a letter copybook (1852-1858) detailing information on both vessels and brokerage firms, containing business letters to a worldwide clientele.